TempoLife › Funkcijas › Herb and spice reference: evidence, dose and interactions › comfrey
Comfrey
Comfrey — ko Eiropas monogrāfija patiesībā apstiprina, kam tas nav paredzēts, forma un cik ilgi to paredzēts lietot, blakusparādības un 1 zāļu mijiedarbība, kas tam dokumentēta.
Šī ir uzziņu lapa, nevis diagnoze un nevis recepte. Augu izcelsmes produkti ir īsta farmakoloģija: tiem ir iedarbība, blakusparādības un mijiedarbība ar medikamentiem. Pastāstiet savam ārstam un farmaceitam par visu, ko lietojat, tostarp par tējām un uztura bagātinātājiem, un nekad nepārtrauciet un nemainiet nozīmētu medikamentu tāpēc, ka esat šeit kaut ko izlasījis.
Kas tas ir
Symphytum officinale L. — root and leaf
Vietējie nosaukumi reģionā, ko apkalpo šī vietne:varemerohi (ET) · rohtoraunioyrtti (FI) · окопник (RU).
Šeit grupēts sadaļā Where the harm is. Regulējuma nostāja:External use only, with limits; oral preparations are not acceptable in the EU.
Ko pierādījumi apstiprina
Reģistrētā indikācija:External use on unbroken skin for bruises, sprains and strains, in pyrrolizidine-alkaloid-depleted preparations.
Comfrey is the clearest case of a traditional remedy that modern chemistry ruled out for internal use. It contains pyrrolizidine alkaloids, which the liver converts into reactive compounds that damage the small hepatic veins and cause hepatic veno-occlusive disease (sinusoidal obstruction syndrome); they are also genotoxic and carcinogenic in animal studies. Oral comfrey preparations were withdrawn in Europe decades ago on that basis. Externally, comfrey creams and ointments for bruises and sprains remain in use and have reasonable trial support for pain relief, but regulators restrict them to alkaloid-depleted preparations, intact skin only, and a limited number of days of use per year — because pyrrolizidine alkaloids are absorbed through skin. The wider lesson is that this is not a comfrey-only problem: the same alkaloids occur in ragwort, borage, butterbur and coltsfoot, and they contaminate herbal teas and honey when alkaloid-containing weeds are harvested with the crop. European food law sets maximum levels for pyrrolizidine alkaloids in herbal teas, teas, certain herbs and food supplements for exactly that reason.
D — Popular claim unsupported, or safety dominates The better trials are negative, or the substance appears in the literature mainly for the harm it has caused.
Kam tas nav paredzēts
Swallowing, in any form, including comfrey tea and "knitbone" infusions. Also not for open wounds, broken skin or grazes.
Forma, stiprums un cik ilgi
Creams, ointments and gels of alkaloid-depleted root or leaf extract, for external use on unbroken skin.
Ilgums.Limited courses, and a limited total number of days per year — the restriction is on cumulative exposure, not on any single application.
Šajā lapā apzināti nav neviena skaitļa gramos. Auga daļa, ekstrakcijas šķīdinātājs un izejvielas un ekstrakta attiecība kopā nosaka preparātu, un skaitlis, kas ņemts no viena, neapraksta citu. Pamatojums ir izklāstīts centrālajā lapā; jums piemērojamais daudzums ir tas, kas uzdrukāts uz iepakojuma, ko turat rokās, un farmaceits to izlasīs kopā ar jums.
Blakusparādības
Externally, occasional skin irritation and contact allergy. Internally, liver injury that can be severe and irreversible.
Kam no tā jāizvairās
Never in pregnancy or while breastfeeding. Not on children. Not with existing liver disease.
Mijiedarbība ar zālēm
| Medikaments vai viela | Kas ir aprakstīts |
|---|---|
| Anything else that stresses the liver | Anything else that burdens the liver — alcohol, other pyrrolizidine-containing plants, medicines with a hepatic signal — adds to the same target organ. |
Apgrieztais skatījums — sākt nevis no auga, bet no zālēm — ir atrodams zāļu, pārtikas un alkohola mijiedarbību rokasgrāmata, un apkopots par katru augu šajā vietnē.
Avoti:European Medicines Agency — Committee on Herbal Medicinal Products (HMPC), European Union herbal monographs · LiverTox: Clinical and Research Information on Drug-Induced Liver Injury (NIDDK, National Institutes of Health)· pārbaudīts2026-09-06
Bieži uzdotie jautājumi
Kam izmanto comfrey?
External use on unbroken skin for bruises, sprains and strains, in pyrrolizidine-alkaloid-depleted preparations. Comfrey is the clearest case of a traditional remedy that modern chemistry ruled out for internal use. It contains pyrrolizidine alkaloids, which the liver converts into reactive compounds that damage the small hepatic veins and cause hepatic veno-occlusive disease (sinusoidal obstruction syndrome); they are also genotoxic and carcinogenic in animal studies. Oral comfrey preparations were withdrawn in Europe decades ago on that basis. Externally, comfrey creams and ointments for bruises and sprains remain in use and have reasonable trial support for pain relief, but regulators restrict them to alkaloid-depleted preparations, intact skin only, and a limited number of days of use per year — because pyrrolizidine alkaloids are absorbed through skin. The wider lesson is that this is not a comfrey-only problem: the same alkaloids occur in ragwort, borage, butterbur and coltsfoot, and they contaminate herbal teas and honey when alkaloid-containing weeds are harvested with the crop. European food law sets maximum levels for pyrrolizidine alkaloids in herbal teas, teas, certain herbs and food supplements for exactly that reason.
Vai comfrey darbojas?
Novērtēts D šeit: The better trials are negative, or the substance appears in the literature mainly for the harm it has caused. Swallowing, in any form, including comfrey tea and "knitbone" infusions. Also not for open wounds, broken skin or grazes.
Cik daudz comfrey man vajadzētu lietot?
Šajā atsauces materiālā nav norādīti gramu skaitļi, jo tie nav pārnesami starp dažāda ekstrakta stipruma preparātiem. Godīgi var pateikt tikai formu un ilgumu:Creams, ointments and gels of alkaloid-depleted root or leaf extract, for external use on unbroken skin. Limited courses, and a limited total number of days per year — the restriction is on cumulative exposure, not on any single application.
Kādas ir comfrey blakusparādības?
Externally, occasional skin irritation and contact allergy. Internally, liver injury that can be severe and irreversible.
Vai comfrey mijiedarbojas ar medikamentiem?
Jā — dokumentētsLiver load. Katrs no tiem ir aprakstīts šajā lapā, ar saiti uz zāļu puses atsauci, kur tāda ir.
Citi:where the harm is
Turiet visu sarakstu vienā vietā
TempoLife ieraksta uztura bagātinātājus līdzās ēdienam, miegam un patiesajai pašsajūtai — tāpēc atbilde uz jautājumu "ko jūs lietojat?" ir ekrāns, nevis minējums.