TempoLife › Funkcijos › Herb and spice reference: evidence, dose and interactions › comfrey
Comfrey
Comfrey — ką Europos monografija iš tikrųjų pagrindžia, kam jis nėra skirtas, forma ir kiek laiko jį numatyta naudoti, šalutinis poveikis ir 1 vaisto sąveika, dokumentuota jam.
Tai informacinis tinklalapis, o ne diagnozė ir ne receptas. Augaliniai produktai yra tikra farmakologija: jie turi veikimą, šalutinį poveikį ir sąveikas su vaistais. Pasakykite savo gydytojui ir vaistininkui apie viską, ką vartojate, įskaitant arbatas ir papildus, ir niekada nenutraukite bei nekeiskite paskirto vaisto dėl to, ką čia perskaitėte.
Kas tai yra
Symphytum officinale L. — root and leaf
Vietiniai pavadinimai regione, kurį aptarnauja ši svetainė:varemerohi (ET) · rohtoraunioyrtti (FI) · окопник (RU).
Čia sugrupuota skiltyje Where the harm is. Reguliavimo pozicija:External use only, with limits; oral preparations are not acceptable in the EU.
Ką įrodymai patvirtina
Registruota indikacija:External use on unbroken skin for bruises, sprains and strains, in pyrrolizidine-alkaloid-depleted preparations.
Comfrey is the clearest case of a traditional remedy that modern chemistry ruled out for internal use. It contains pyrrolizidine alkaloids, which the liver converts into reactive compounds that damage the small hepatic veins and cause hepatic veno-occlusive disease (sinusoidal obstruction syndrome); they are also genotoxic and carcinogenic in animal studies. Oral comfrey preparations were withdrawn in Europe decades ago on that basis. Externally, comfrey creams and ointments for bruises and sprains remain in use and have reasonable trial support for pain relief, but regulators restrict them to alkaloid-depleted preparations, intact skin only, and a limited number of days of use per year — because pyrrolizidine alkaloids are absorbed through skin. The wider lesson is that this is not a comfrey-only problem: the same alkaloids occur in ragwort, borage, butterbur and coltsfoot, and they contaminate herbal teas and honey when alkaloid-containing weeds are harvested with the crop. European food law sets maximum levels for pyrrolizidine alkaloids in herbal teas, teas, certain herbs and food supplements for exactly that reason.
D — Popular claim unsupported, or safety dominates The better trials are negative, or the substance appears in the literature mainly for the harm it has caused.
Kam tai nėra skirta
Swallowing, in any form, including comfrey tea and "knitbone" infusions. Also not for open wounds, broken skin or grazes.
Forma, stiprumas ir kiek ilgai
Creams, ointments and gels of alkaloid-depleted root or leaf extract, for external use on unbroken skin.
Trukmė.Limited courses, and a limited total number of days per year — the restriction is on cumulative exposure, not on any single application.
Šiame puslapyje tyčia nėra jokio skaičiaus gramais. Augalo dalis, ekstrakcijos tirpiklis ir žaliavos bei ekstrakto santykis kartu apibrėžia preparatą, o iš vieno paimtas skaičius neaprašo kito. Pagrindimas išdėstytas pagrindiniame puslapyje; jums taikomas kiekis yra tas, kuris atspausdintas ant pakuotės, kurią laikote rankose, o vaistininkas jį perskaitys su jumis.
Šalutinis poveikis
Externally, occasional skin irritation and contact allergy. Internally, liver injury that can be severe and irreversible.
Kam reikėtų to vengti
Never in pregnancy or while breastfeeding. Not on children. Not with existing liver disease.
Sąveika su vaistais
| Vaistas ar medžiaga | Kas aprašyta |
|---|---|
| Anything else that stresses the liver | Anything else that burdens the liver — alcohol, other pyrrolizidine-containing plants, medicines with a hepatic signal — adds to the same target organ. |
Atvirkštinis vaizdas — pradėti ne nuo augalo, o nuo vaisto — yra vaistų, maisto ir alkoholio sąveikų žinynas, o apibendrinta apie kiekvieną augalą šioje svetainėje.
Šaltiniai:European Medicines Agency — Committee on Herbal Medicinal Products (HMPC), European Union herbal monographs · LiverTox: Clinical and Research Information on Drug-Induced Liver Injury (NIDDK, National Institutes of Health)· patikrinta2026-09-06
Dažnai užduodami klausimai
Kam naudojamas comfrey?
External use on unbroken skin for bruises, sprains and strains, in pyrrolizidine-alkaloid-depleted preparations. Comfrey is the clearest case of a traditional remedy that modern chemistry ruled out for internal use. It contains pyrrolizidine alkaloids, which the liver converts into reactive compounds that damage the small hepatic veins and cause hepatic veno-occlusive disease (sinusoidal obstruction syndrome); they are also genotoxic and carcinogenic in animal studies. Oral comfrey preparations were withdrawn in Europe decades ago on that basis. Externally, comfrey creams and ointments for bruises and sprains remain in use and have reasonable trial support for pain relief, but regulators restrict them to alkaloid-depleted preparations, intact skin only, and a limited number of days of use per year — because pyrrolizidine alkaloids are absorbed through skin. The wider lesson is that this is not a comfrey-only problem: the same alkaloids occur in ragwort, borage, butterbur and coltsfoot, and they contaminate herbal teas and honey when alkaloid-containing weeds are harvested with the crop. European food law sets maximum levels for pyrrolizidine alkaloids in herbal teas, teas, certain herbs and food supplements for exactly that reason.
Ar comfrey veikia?
Įvertinta D čia: The better trials are negative, or the substance appears in the literature mainly for the harm it has caused. Swallowing, in any form, including comfrey tea and "knitbone" infusions. Also not for open wounds, broken skin or grazes.
Kiek comfrey turėčiau vartoti?
Šiame žinyne gramų skaičiai nenurodomi, nes jie neperkeliami tarp skirtingo ekstrakto stiprumo preparatų. Sąžiningai galima nurodyti tik formą ir trukmę:Creams, ointments and gels of alkaloid-depleted root or leaf extract, for external use on unbroken skin. Limited courses, and a limited total number of days per year — the restriction is on cumulative exposure, not on any single application.
Kokie yra comfrey šalutiniai poveikiai?
Externally, occasional skin irritation and contact allergy. Internally, liver injury that can be severe and irreversible.
Ar comfrey sąveikauja su vaistais?
Taip — dokumentuotaLiver load. Kiekvienas iš jų aprašytas šiame puslapyje, su nuoroda į vaisto pusės žinyną, kur toks yra.
Kiti:where the harm is
Visą sąrašą laikykite vienoje vietoje
TempoLife fiksuoja maisto papildus kartu su maistu, miegu ir tikrąja savijauta — todėl atsakymas į klausimą "ką vartojate?" yra ekranas, o ne spėjimas.