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Kava

Kava — ce que la monographie européenne soutient réellement, ce à quoi ce n’est pas destiné, la forme et la durée prévue, les effets indésirables, et le 3 interaction médicamenteuses documentée.

Dnote de preuve —popular claim unsupported, or safety dominates
Restreint dans l’UEEU regulatory status
3medicine interactions listed

Ceci est une page de référence, pas un diagnostic ni une ordonnance. Les produits à base de plantes sont de la vraie pharmacologie : effets, effets indésirables et interactions. Dites à votre médecin et à votre pharmacien tout ce que vous prenez, thés et compléments compris, et n’arrêtez ni ne changez jamais un médicament prescrit à cause de ce que vous lisez ici.

Ce que c’est

Piper methysticum G.Forst. — root and rhizome

Groupé ici sous Where the harm is. Position réglementaire :Withdrawn, suspended or restricted as a medicine in much of Europe after reports of severe liver injury.

Ce que les preuves soutiennent

L’indication enregistrée :It was marketed for anxiety. It is included here as a boundary, not a recommendation.

Kava beverages have a long cultural history in the Pacific islands. The European story is different: standardised kava extracts marketed for anxiety in the 1990s were withdrawn or suspended in several countries after reports of severe hepatotoxicity, including liver failure requiring transplantation. Regulatory positions have shifted back and forth in the decades since and availability differs by country, which is exactly why an internet order is a poor way to settle the question. The awkward part of the case is that the trials suggested a genuine anxiety-reducing effect — an effective product with a rare, catastrophic harm is a much harder judgement than an ineffective one, and that is the honest shape of the kava file rather than a simple story of quackery. Preparation matters too: traditional water-based preparations of the peeled rootstock differ from the acetone and ethanol extracts that reached European shelves.

D — Popular claim unsupported, or safety dominates The better trials are negative, or the substance appears in the literature mainly for the harm it has caused.

Ce à quoi ce n’est pas destiné

Anxiety disorders, which have treatments with far better-characterised risk. Do not import it to self-treat.

Forme, force et durée

Traditional water-based root beverages; ethanol and acetone extracts in capsules, which are the preparations associated with the liver reports.

Durée.Not applicable — no European regulator is recommending a course.

Aucun chiffre en grammes n’apparaît sur cette page exprès. La partie de plante, le solvant d’extraction et le rapport drogue-extrait définissent ensemble une préparation, et un nombre pris à l’une ne décrit pas l’autre. Le raisonnement est exposé sur le hub ; la quantité qui s’applique à vous est celle imprimée sur le paquet que vous tenez, et un pharmacien la lira avec vous.

Effets indésirables

Liver injury, which is rare but has been severe and occasionally fatal. Regular heavy use causes a dry, scaly skin condition known as kava dermopathy. Drowsiness and impaired driving, markedly worsened by alcohol.

Qui devrait l’éviter

Avoid entirely with any liver disease, in pregnancy and while breastfeeding, and before driving.

Interactions avec les médicaments

Interactions nommées dans les monographies UE, les informations produit et les fiches NIH. Les liens mènent à la page côté médicament de ce groupe.
Médicament ou substanceCe qui est décrit
AlcoholThe combination increases both sedation and the liver risk, and impaired driving with kava plus alcohol is documented.
Sleeping tablets, benzodiazepines and sedating antihistaminesAdditive sedation with benzodiazepines, sleeping tablets and sedating antihistamines.
Anything else that stresses the liverAnything else with a liver signal — including alcohol and several medicines — should not be stacked with it.

La vue inverse — partir du médicament plutôt que de la plante — est dans la référence des interactions médicaments, aliments et alcool, et résumé pour chaque plante de ce site.

Sources :NIH National Center for Complementary and Integrative Health — herb fact sheets · LiverTox: Clinical and Research Information on Drug-Induced Liver Injury (NIDDK, National Institutes of Health)· vérifié2026-09-06

Questions fréquentes

À quoi sert kava ?

It was marketed for anxiety. It is included here as a boundary, not a recommendation. Kava beverages have a long cultural history in the Pacific islands. The European story is different: standardised kava extracts marketed for anxiety in the 1990s were withdrawn or suspended in several countries after reports of severe hepatotoxicity, including liver failure requiring transplantation. Regulatory positions have shifted back and forth in the decades since and availability differs by country, which is exactly why an internet order is a poor way to settle the question. The awkward part of the case is that the trials suggested a genuine anxiety-reducing effect — an effective product with a rare, catastrophic harm is a much harder judgement than an ineffective one, and that is the honest shape of the kava file rather than a simple story of quackery. Preparation matters too: traditional water-based preparations of the peeled rootstock differ from the acetone and ethanol extracts that reached European shelves.

Est-ce que kava marche ?

Noté ici D : The better trials are negative, or the substance appears in the literature mainly for the harm it has caused. Anxiety disorders, which have treatments with far better-characterised risk. Do not import it to self-treat.

Combien de kava dois-je prendre ?

Cette référence n’imprime pas de chiffres en grammes, car ils ne se transférent pas entre préparations de force d’extrait différente. Ce qu’on peut dire honnêtement, c’est la forme et la durée :Traditional water-based root beverages; ethanol and acetone extracts in capsules, which are the preparations associated with the liver reports. Not applicable — no European regulator is recommending a course.

Quels sont les effets indésirables de kava ?

Liver injury, which is rare but has been severe and occasionally fatal. Regular heavy use causes a dry, scaly skin condition known as kava dermopathy. Drowsiness and impaired driving, markedly worsened by alcohol.

Est-ce que kava interagit avec des médicaments ?

Oui — documenté pourAlcohol, Sedatives, Liver load. Chacune est décrite sur cette page, avec un lien vers la référence côté médicament s’il en existe une.

Autres danswhere the harm is

Comfrey

External use on unbroken skin for bruises, sprains and strains, in pyrrolizidine-alkaloid-depleted preparations.

NoteD · Liver load

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